Pharmaceutical preparations and illicit drugs as contaminating substances of surface and wastewater

Determination of acetylsalicylic acid and related substances in pharmaceutical preparations and bulk drugs by capillary electrophoresis

Micellar electrokinetic chromatography (MEKC) using sodium dodecyl sulphate (SDS) in separation buffer has been employed for the separation and determination of acetylsalicylic acid and related compounds in tablets and bulk drugs. Base line separation was achieved by using 12.5 mM sodiumtetraborate decahydrate, 15 mM boric acid (pH 9.0) and 50 mM SDS. Analytical characteristics such as migratio...

Spectrophotometric Determination of Thiols in Pure Substances and Pharmaceutical Preparations

A spectrophotometric method for determination of mesna (MA), 6-mercaptopurine (MP), 6-thioguanine (TG), and 6-propyl-2-thiouracil (PTU) has been developed. The method was based on the reaction of thiouracils with N,N-dimethyl-p-phenylenediamine (DMPD) in acidic solution in the presence of the Fe3+ ion, an oxidising agent. Absorbance of the obtained coloured products was measured at the correspo...

The Extra Pharmacopœia of Unofficial Drugs and Chemical Pharmaceutical Preparations

Linking with Biam: Searching for Drugs and Pharmaceutical Substances

The quantity of biomedical publications is growing at an exponential rate. With such explosive growth of the content, it is more and more difficult to locate, retrieve and manage the resulting information. This is why text mining has become a necessity. The main goal of biomedical research is to put knowledge to practical use in the form of diagnoses, prevention, and treatment. It is important ...

Rhabdomyolysis Syndrome in Alcohol, Psychotropic Drugs, and Illicit Substance Poisonings

Background: Rhabdomyolysis is one of the major complications of poisoning caused by alcohol, narcotics, and psychotropic substances acute toxicity, which might lead to acute renal failure and even death. This study aimed to evaluate clinical and laboratory findings of rhabdomyolysis syndrome in poisoning patients who were admitted to poisoning ward of Farshchian Hospital of Hamadan, Iran. Meth...